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Ca2+-calmodulin regulates receptor-operated Ca2+ entry activity of TRPC6 in HEK-293 cells

✍ Scribed by G Boulay

Book ID: 114118475
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 157 KB
Volume: 32
Category: Article
ISSN: 0143-4160
DOI: 10.1016/s0143416002001550

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## Abstract Prostate smooth muscle cells predominantly express α1‐adrenoceptors (α1‐AR). α1‐AR antagonists induce prostate smooth muscle relaxation and therefore they are useful therapeutic compounds for the treatment of benign prostatic hyperplasia symptoms. However, the Ca^2+^ entry pathways asso