Ca 2+ /Calmodulin-dependent protein kinase IV and calcium signaling
โ Scribed by Kristin A Anderson; Christopher D Kane
- Book ID
- 110273443
- Publisher
- Springer Netherlands
- Year
- 1998
- Tongue
- English
- Weight
- 99 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1572-8773
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๐ SIMILAR VOLUMES
Ca 2ฯฉ /calmodulin-dependent protein kinase IV (CaM kinase IV) is a multifunctional enzyme that is abundantly present in the nuclei of neurons. We report the properties of phosphorylation and activation of CaM kinase IV in comparison to CaM kinase II in cultured rat hippocampal neurons. Phosphorylati
## Abstract Calcium/calmodulinโdependent protein kinase IV (CaMKIV) plays a key role in the regulation of calciumโdependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We report here that: (a) a bioinformatic ana
DEAE-cellulose column chromatography of Neurospora crassa soluble mycelial extracts leads to the resolution of three major protein kinase activity peaks designated PKI, PKII, and PKIII. PKII activity is stimulated by Ca2+ and Neurospora or brain calmodulin. Maximal stimulation was observed at 2 micr