C7 complement deficiency in an Israeli Arab village
β Scribed by Behar, Doron ;Schlesinger, Menachem ;Halle, David ;Ben-Ami, Haim ;Edoute, Yehouda ;Shahar, Eduardo ;Kasis, Imad ;Shihab, Shihab ;Elstein, Deborah ;Zimran, Ari ;Mandel, Hanna
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 110 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A woman with systemic lupus erythematosus (SLE) was found to have undetectable serum total complement (C) activity with marked reductions in levels of several C components. Recognition of rising C4, C3, and C5 levels coupled with sustained absence of hemolytic activity led to studies of
A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i
The rare allele ADA6, was detected in seven members of an Arab Moslem family from northern Israel. All had the electrophoretic pattern of heterozygotes ADA6--1. This phenotype was formerly described in a small German family. The individuals examined in this study are a small branch of a much larger
It is common among Israeli Arabs who live in the villages to prefer consanguineous marriages, particularly among fwst cousins. In addition, such villages are populated by a few (< 20) original families, and inter-familyhntervillage marriages are infrequent. The purpose of this study was to examine t