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C609T polymorphism of the NAD(P)H:quinone oxidoreductase I gene does not significantly affect susceptibility for esophageal adenocarcinoma

✍ Scribed by Burkhard H. A. von Rahden; Hubert J. Stein; Rupert Langer; Claus W. von Weyhern; Esther Schenk; Carl Döring; J. Rüdiger Siewert; Heinz Höfler; Mario Sarbia


Publisher
John Wiley and Sons
Year
2004
Tongue
French
Weight
57 KB
Volume
113
Category
Article
ISSN
0020-7136

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Association between NAD(P)H: Quinone oxi
✍ Mario Sarbia; Monika Bitzer; David Siegel; David Ross; Wolfgang A. Schulz; Raine 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 128 KB

## Abstract NQO1 is an antioxidant enzyme, important in the detoxification of environmental carcinogens. A single nucleotide polymorphism (C→T) at position 609 of the __NQO1__ cDNA has been associated with susceptibility to tumours induced by chemical carcinogens. In our case‐control study, we dete