𝔖 Bobbio Scriptorium
✦   LIBER   ✦

C2 monitoring of cyclosporine in de novo liver transplant recipients: The clinician's perspective

✍ Scribed by Federico Villamil; Stephen Pollard


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
197 KB
Volume
10
Category
Article
ISSN
1527-6465

No coin nor oath required. For personal study only.

✦ Synopsis


Abbreviations: AUC 0 -6 , area under the curve for the first six hours post-dose; AUC 0 -12 , area under the curve for the first twelve hours post-dose; C 0, trough blood concentration; C 2, blood concentration at 2 hours after dose; C 4 , blood concentration at 4 hours after dose; C 6 , blood concentration at 6 hours after dose; CsA, cyclosporine; ME, microemulsion; MMF, mycophenolate mofetil.


πŸ“œ SIMILAR VOLUMES


Increased incidence of early de novo can
✍ Angela S. W. Tjon; Jerome Sint Nicolaas; Jaap Kwekkeboom; Robert A. de Man; Geer πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 304 KB πŸ‘ 1 views

The goal of this study was to determine the risk factors for de novo cancer after liver transplantation (LTx). Retrospective analyses were performed in 385 LTx patients who underwent transplantation between 1986 and 2007. In total, 50 (13.0%) recipients developed de novo malignancy. The cumulative i

A randomized, prospective, pharmacoecono
✍ Surendra Shenoy; Karen L. Hardinger; Jeffrey Crippin; Kevin Korenblat; Mauricio πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 293 KB πŸ‘ 1 views

Two-hour postdose cyclosporine (C2) monitoring is becoming an accepted method of therapeutic drug monitoring, although it is not known whether C2 monitoring is superior to tacrolimus (FK)-based immunosuppression. The purpose of this trial was to compare the safety, efficacy, and pharmacoeconomics of

The immunological monitoring of alloreac
✍ Raymond Reding; JΓ©rΓ©mie Gras; Dinh Quang Truong; GrΓ©goire WieΓ«rs; Dominique Lati πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 148 KB πŸ‘ 1 views

The aim of this work is to review the current knowledge in the field of immunological monitoring of allogenic responsiveness in clinical liver transplantation. When compared to other solid-organ transplants, liver allografts are considered as immunologically privileged, and, accordingly, constitute

Improved cyclosporine bioavailability in
✍ Cooney, Gerard F. ;Dunn, Stephen P. ;Sommerauer, John ;Lindsay, Christine ;McDia πŸ“‚ Article πŸ“… 1999 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 124 KB

Black transplant recipients are associated with low cyclosporine bioavailability, which may contribute to the poorer clinical outcomes observed with these patients. In this analysis, we compared cyclosporine exposure in black (n ‫؍‬ 9) and nonblack (n ‫؍‬ 18) pediatric maintenance liver transplant r

Safety, tolerability, and efficacy of ev
✍ Gary Levy; Heinz Schmidli; Jeffrey Punch; Elizabeth Tuttle-Newhall; David Mayer; πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 128 KB πŸ‘ 1 views

Everolimus is a macrolide immunosuppressive agent with known consistent absorption. In this double-blind study, we examined the safety and tolerability of everolimus vs. placebo in de novo liver transplant recipients. One hundred and nineteen liver allograft recipients were randomized to 1 of 4 grou