C1q–calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease
✍ Scribed by Xiaoguang Luo; Gregory A Weber; Jialin Zheng; Howard E Gendelman; Tsuneya Ikezu
- Book ID
- 114137849
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 408 KB
- Volume
- 135
- Category
- Article
- ISSN
- 0165-5728
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## Abstract Glutathione (GSH) is an important endogenous antioxidant found in millimolar concentrations in the brain. GSH levels have been shown to decrease with aging. Alzheimer's disease (AD) is a neurodegenerative disorder associated with aging and oxidative stress. Aβ(1–42) has been shown to in
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