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C13 - Endothelial injury in the TGR(mRen2)27

✍ Scribed by WB Strawn; RH Dean; D Ganten; CM Ferrario


Book ID
116155922
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
165 KB
Volume
8
Category
Article
ISSN
0895-7061

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Reduction of cardiac hypertrophy in TGR(
✍ Manfred BΓΆhm; Andrea Lippoldt; Wolfgang Wienen; Detlev Ganten; Michael Bader πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 378 KB

TGR(mREN2)27 is a transgenic rat harboring the murine Ren-2 gene and exhibit fulminant hypertension and marked heart hypertrophy. In order to study the role of angiotensin II in the increase of cardiac mass, these animals were treated with antihypertensive and non-antihypertensive doses of the angio