and specific binding sites for the A~ antagonist [3H]DPCPX. The rank order of affinities of various adenosine egonists and antagonists confirmed the identity of the cDNA clone. Binding of agonists was sensitive to the presence of the nonhydrelyzable GTP analog, GppNHp. In edenylyl cyclase essays, ad
C02 Regulation of cardiac adenosine metabolism
β Scribed by J. Schrader
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 107 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0985-0562
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π SIMILAR VOLUMES
## RESUM]~S DES COMMUNICATIONS : AD]~NOS1NE thus, tissue specific differences in adenosine receptor subtypes that have been proposed on the bases of subtle pharmacological differences in ligand binding have not yet been identified. All of the adenosine receptors couple to GTP binding proteins and.
## ADI~NOSINE changes in energy status -whether this reflects shortcoming,'," of the methods or a failure of the hypothesis remains to be resolved. If cytosolic ADP and AMP concentrations are elevated dudng net A'rP catabolism, then the ADP-stimulated AMP-selective 5'-nucleofidase that has been p