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C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells

✍ Scribed by Hiratsuka, S.; Duda, D. G.; Huang, Y.; Goel, S.; Sugiyama, T.; Nagasawa, T.; Fukumura, D.; Jain, R. K.


Book ID
121743995
Publisher
National Academy of Sciences
Year
2010
Tongue
English
Weight
886 KB
Volume
108
Category
Article
ISSN
0027-8424

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## Abstract Myostatin is a negative regulator of skeletal muscle mass. The pathways employed in modulating myostatin gene expression are scarcely known. We aimed to determine the signaling pathway of myostatin induction by a histone deacetylase (HDAC) inhibitor–trichostatin A (TSA) in differentiate