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C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity

✍ Scribed by Urban Švajger; Marko Anderluh; Matjaž Jeras; Nataša Obermajer


Book ID
113528407
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
502 KB
Volume
22
Category
Article
ISSN
0898-6568

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The C-type lectin DC-SIGN (CD209) is an
✍ Alessandra Cambi; Karlijn Gijzen; I. Jolanda M. de Vries; Ruurd Torensma; Ben Jo 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 242 KB

## Abstract Dendritic cells (DC) that express the type II C‐type lectin DC‐SIGN (CD209) are located in the submucosa of tissues, where they mediate HIV‐1 entry. Interestingly, the pathogen __Candida albicans,__the major cause of hospital‐acquired fungal infections, penetrates at similar submucosal