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C-terminal sequencing of protein : A novel partial acid hydrolysis and analysis by mass spectrometry

✍ Scribed by Akira TSUGITA; Keiji TAKAMOTO; Masaharu KAMO; Hiromoto IWADATE


Book ID
115129355
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
402 KB
Volume
206
Category
Article
ISSN
1432-1327

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## Abstract We report the design, chemical synthesis, and structural and functional characterization of a novel reagent for protein sequence analysis by the Edman degradation, yielding amino acid derivatives rapidly detectable at high sensitivity by ion‐evaporation mass spectrometry. We demonstrate