C-Peptide/Creatinine Ratio in Early Morning Urine as an Indicator of Residual B-Cell Function in Insulin-Dependent Diabetes

Increased proinsulin levels as an early

Increased proinsulin levels as an early indicator of B-cell dysfunction in non-diabetic twins of Type 1 (insulin-dependent) diabetic patients

✍ D. A. Heaton; B. A. Millward; I. P. Gray; Y. Tun; C. N. Hales; D. A. Pyke; R. D. 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 317 KB

Glucose tolerance and insulin secretion were studied in two groups of non-diabetic identical twins of recently-diagnosed Type 1 (insulin-dependent) diabetic patients: (1) a group of 5 twins with islet cell antibodies, and (2) a group of 6 twins without. Despite similar fasting glucose, insulin and C