𝔖 Bobbio Scriptorium
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c-Myc-regulated microRNAs modulate E2F1 expression

✍ Scribed by O'Donnell, Kathryn A.; Wentzel, Erik A.; Zeller, Karen I.; Dang, Chi V.; Mendell, Joshua T.


Book ID
109894360
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
339 KB
Volume
435
Category
Article
ISSN
0028-0836

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## Abstract Phosphatidylinositol 3‐kinase (PI3K) signaling controls survival and proliferation of cancer cells and is activated in around 60% of pancreatic ductal adenocarcinomas (PDACs). Although not entirely clarified, PI3K signaling is linked to cell cycle progression of PDAC cells. In this stud