c-myb has a character of oxidative stress resistance in aged human diploid fibroblasts: regulates SAPK/JNK and Hsp60 pathway consequently

Oxidative stress resistance through bloc

Oxidative stress resistance through blocking Hsp60 translocation followed by SAPK/JNK inhibition in aged human diploid fibroblasts

✍ Young-Hee Lee; Bhattarai Govinda; Jae-Cheol Kim; Tae-Il Kim; Nan-Hee Lee; Jung-C 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB

## Abstract The stress‐activated protein kinase/__c__‐Jun __N__‐terminal kinase (SAPK/JNK) pathway is a well‐known senescence‐related stress activated protein kinase. Multiple environmental stresses induce programmed cell death, such as apoptosis. Normal human diploid fibroblast (HDF) cells have a