c-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens
β Scribed by Willmore-Payne, Carlynn ;Layfield, Lester J. ;Holden, Joseph A.
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 181 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Gastrointestinal stromal tumor (GIST) is the designation for a major subset of gastrointestinal mesenchymal tumors that histologically, immunocytochemically, and genetically differ from leiomyomas, leiomyosarcomas, and schwannomas. GISTs derive from the interstitial cells of Cajal and,
## Abstract The diagnosis of gastrointestinal stromal tumors (GISTs) is generally established on histopathologic examination of surgical specimens. Fineβneedle aspiration (FNA), performed under the guidance of ultrasound or computed tomography, is being used with increasing frequency in an attempt