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c-Kit and CD38 are expressed by long-term reconstituting hematopoietic cells present in the murine yolk sac

✍ Scribed by Ramzi N Dagher; Kelly Hiatt; Christie Traycoff; Edward F Srour; Mervin C Yoder; Herman B Wells

Book ID: 119754662
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 125 KB
Volume: 4
Category: Article
ISSN: 1083-8791
DOI: 10.1053/bbmt.1998.v4.pm9763109

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## Abstract The murine white (W) spotting locus is the site of the c‐kit gene and encodes a tyrosine kinase receptor while the complementary Steel (Sl) iocus encodes its ligand. Mutations at either locus have profound effects on hematopoiesis, particularly erythroid and mast cell proliferation. We