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c-Ki-ras mutations in colorectal adenocarcinomas from a country with a rapidly changing colorectal cancer incidence

โœ Scribed by Tang, W-Y; Elnatan, J; Lee, Y-S; Goh, H-S; Smith, D R


Book ID
110002470
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
103 KB
Volume
81
Category
Article
ISSN
0007-0920

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Ki-ras MUTATIONS IN ADENOMAS: A CHARACTE
โœ MORRIS, ROBERT G.; CURTIS, LUCY J.; ROMANOWSKI, PIOTR; HARDCASTLE, JACK D.; JENK ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 652 KB

Activating mutations in the Ki-ras2 oncogene are frequently observed in sporadic colorectal adenomas and their incidence is reported to rise in large and tubulovillous adenomas to values close to those in carcinomas. This study shows that this property is a feature of adenomas growing in large bowel