✦ LIBER ✦
C-hydroxyarylation of tetraphenylporphyrin - convenient introduction of a functionality which is oriented towards the porphyrin centre
✍ Scribed by Maxwell J. Crossley; Jeffrey J. Gosper; Lionel G. King
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 291 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
2-Nitro-5,10,15,20-tetraphenylporphyrin 1 and its copper and nickel(I1) chelates, 2 and 3 respectively, undergo nucleophilic substitution with sodium aryloxides in the corresponding phenol to afford mainly the 2-(o-hydroxyphenyl)porphyrin derivatives. This functionality is useful because it directs subsequently-attached substituents towards the porphyrin centre, as is demonstrated by a comparison of the average conformations of the 9Zoctadecenoic acid esters 14 and 15.