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c-erbB2/neu gene and chromosome 17 analysis in breast cancer by FISH on archival cytological fine-needle aspirates

✍ Scribed by Mezzelani, A; Alasio, L; Bartoli, C; Bonora, M G; Pierotti, M A; Rilke, F; Pilotti, S

Book ID: 110002204
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 121 KB
Volume: 80
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6690387

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## BACKGROUND. Fine-needle sampling, although a practical and noninvasive method of tissue acquisition, has rarely been used for HER-2/neu fluorescent in situ hybridization (FISH). To assess HER-2/neu gene amplification in mammary carcinoma, FISH signals on cytology and corresponding tissue biopsie