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c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination

✍ Scribed by Thomas Ohrt; Annalisa Mancini; Teruko Tamura; Rainer Niedenthal


Book ID
113527635
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
583 KB
Volume
16
Category
Article
ISSN
0898-6568

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p105CasL (CasL) is a recently identified signaling molecule closely related to the p130Cas (Crk-associated substrate) docking protein. CasL has a single Src homology (SH) 3 domain in its N-terminal portion followed by multiple consensus motifs for binding to SH2 domains. Like original p130Cas, CasL