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C- and N-terminal residue effect on peptide derivatives' antagonism toward the formyl-peptide receptor

✍ Scribed by Alessandro Dalpiaz; Maria E. Ferretti; Gianni Vertuani; Serena Traniello; Angelo Scatturin; Susanna Spisani

Book ID
114014546
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
277 KB
Volume
436
Category
Article
ISSN
0014-2999

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## Abstract Transmembrane domains (TMDs) of G‐protein coupled receptors (GPCRs) have very low water solubility and often aggregate during purification and biophysical investigations. To circumvent this problem many laboratories add oligolysines to the __N__‐ and __C__‐termini of peptides that corre