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c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

โœ Scribed by Furstoss, O.


Book ID
111749039
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
395 KB
Volume
21
Category
Article
ISSN
0261-4189

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## Abstract Activation of growth factor receptors by ligand binding leads to an increased expression of __cโ€Myc__, a transcriptional regulator for cell proliferation. The activation of transcriptional factors via the activated receptors is thought to be the main role of __cโ€Myc__ gene expression. W