## Abstract Gap junctions are cellular structures which permit direct exchanges of small molecules from cytoplasm to cytoplasm in most of the cells of metazoan organisms. For four decades, it has been observed that the inhibition of this type of intercellular communication is often associated with
β¦ LIBER β¦
Bystander effect in glioblastoma cells with a predominant cytoplasmic localization of connexin43
β Scribed by Cottin, S; Ghani, K; Caruso, M
- Book ID
- 109842553
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 341 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0929-1903
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## Abstract We previously showed that gap junction intercellular communication mediates the bystander effect in anticancer gene therapy with the herpes simplex virus thymidine kinase (HSVβtk) and ganciclovir. Because most cancer cell lines have lost their ability to communicate through gap junction