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Bystander effect from cytosine deaminase and uracil phosphoribosyl transferase genes in vitro: A partial contribution of gap junctions

✍ Scribed by Toshiaki Tanaka; Agnès Duflot-Dancer; Michèle Tiraby; Colette Piccoli; Gérard Tiraby; Hiroshi Yamasaki; Marc Mesnil

Book ID
116335186
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
303 KB
Volume
282
Category
Article
ISSN
0304-3835

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## Abstract ## Background We aimed to evaluate the efficacy of gene‐directed enzyme‐prodrug therapy (GDEPT) using cytosine deaminase in combination with uracil phosphoribosyl transferase (CDUPRT) against intraprostatic mouse androgen‐refractory prostate (RM1) tumors in immunocompetent mice. The pr