𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Bypassing Multidrug Resistance in Cancer Cells with Biodegradable Polymer Capsules

✍ Scribed by Yan Yan; Christopher J. Ochs; Georgina K. Such; Joan K. Heath; Edouard C. Nice; Frank Caruso

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
806 KB
Volume
22
Category
Article
ISSN
0935-9648

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Recent advances in the discovery of flav
Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance
✍ AhcΓ¨ne Boumendjel; Attilio Di Pietro; Charles Dumontet; Denis Barron πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 189 KB

P-glycoprotein (P-gp) is a plasma membrane glycoprotein that confers multidrug resistance on cells by virtue of its ability to exclude cytotoxic drugs in an ATP-dependent manner. The most commonly considered hypothesis is that P-gp acts as an ATP-driven drug-export pump, the mechanism of which is no

p21Waf1/cip1 acts in synergy with bcl-2
p21Waf1/cip1 acts in synergy with bcl-2 to confer multidrug resistance in a camptothecin-selected human lung-cancer cell line
✍ Yongke Zhang; Naoya Fujita; Takashi Tsuruo πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 217 KB πŸ‘ 1 views

The realization that chemotherapeutic agents induce apoptosis raises the concern that tumors resistant to chemotherapy are unable to initiate the apoptotic program. In the present study, we examined the apoptosis-resistance mechanism of a multidrug-resistant cell line, A549/CPT, which was establishe