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Butyric Acid and Its Monosaccharide Ester Induce Apoptosis in the HL-60 Cell Line

✍ Scribed by C. Calabresse; L. Venturini; G. Ronco; P. Villa; C. Chomienne; D. Belpomme

Book ID
118286753
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
484 KB
Volume
195
Category
Article
ISSN
0006-291X

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✍ Adina Aviram; Yael Zimrah; Mali Shaklai; Abraham Nudelman; Ada Rephaeli πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 French βš– 515 KB

## Abstract A butyric acid pro‐drug, pivaloyioxymethyl butyrate, AN‐9, developed in our laboratory, was previously shown to act as a differentiation‐inducing and an anti‐cancer agent. In this study we have shown that both AN‐9 and butyric acid caused a transient hyperacetylation of histones, which