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Busulfan therapy of central nervous system xenografts in athymic mice

โœ Scribed by Aaron, Rosemary H.; Elion, Gertrude B.; Colvin, O. Michael; Graham, Michael; Keir, Steven; Bigner, Darell D.; Friedman, Henry S.


Book ID
120590661
Publisher
Springer
Year
1994
Tongue
English
Weight
530 KB
Volume
35
Category
Article
ISSN
0344-5704

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## Abstract Human malignant lymphoma cells may be readily heterotransplanted into the brains of athymic nude mice. We have examined humoral immune responses to these lymphoma cells and have found a primary cytotoxic IgM and a late cytotoxic IgG response. Nude mice with tumors growing intracerebrall