Cork gnawing in the rat as a screening m
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Gerald T. Pollard; James L. Howard
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Article
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1991
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John Wiley and Sons
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English
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Male Long-Evans rats were individually allowed access to No. 11 corks for 30 min per day. After 30 sessions, the mean amount gnawed away, 0.1 0 g per session, was stable enough to allow drug testing; it reached asymptote at 0.03 g after 140 sessions. Drugs were injected PO 30 min before testing, exc