This book explores the main challenges and trends related to the use of blockchain technology for digital business innovation with the aim of providing practitioners with stimulating insights and ideas. Readers will find a unified survey of current scientific work on blockchain and related phenomena, such as bitcoin, from a range of perspectives, including information systems, technology management, innovation research, computer science, and engineering. In this way, the book links research and industry practices suitable for use by practitioners in their day-to-day activities and also provides an update on what academia may offer in terms of industry proposals. The contents are divided into three parts. After discussion of blockchain technology and management, including impacts on value chains and systems, governance, and security issues, the bitcoin phenomenon and main technological trends in the use of blockchain are addressed. The final part presents examples of business innovation using blockchain that are drawn from across the globe. Throughout, the author adopts a methodologically rigorous approach while ensuring that the text is readily understandable for readers, regardless of their degree of acquaintance with blockchain.