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Burn-activated neutrophils and tumor necrosis factor-α alter endothelial cell actin cytoskeleton and enhance monolayer permeability

✍ Scribed by Keith Wright; Fiemu Nwariaku; Nabil Halaihel; Carl Schulman; Helen L. Yin; Richard H. Turnage

Book ID: 117849287
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 259 KB
Volume: 128
Category: Article
ISSN: 0039-6060
DOI: 10.1067/msy.2000.108215

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## Abstract Tumor necrosis factor‐α (TNF‐α), a proinflammatory cytokine, has long been known to be involved in the pathogenesis of central nervous system infections and of certain neurodegenerative diseases. However, the possible role of the blood‐brain barrier (BBB), the active interface between t