Burkitt's lymphoma and malaria
β Scribed by G. W. Kafuko; Dr. D. P. Burkitt
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- French
- Weight
- 530 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The distribution of Burkitt's lymphoma is related to endemicity of malaria, not only on a worldβwide basis, but also in more detailed studies in East Africa, particularly in Uganda. This geographical association, together with the diminished incidence of AS haemoglobulin in patients with this tumour and the increased susceptibility to lymphoma formation in mice infected with chronic malaria, suggest a causal relationship.
π SIMILAR VOLUMES
Burkitt's lymphoma (BL) has been defined on the basis of its characteristic cytomorphology. Although histologically identical, endemic BL and sporadic BL are distinct clinico-anatomical entities. Their morphological identity probably relates to similar chromosomal translocations in both tumours, res
## Abstract Of 109 patients with histologically confirmed Burkitt's lymphoma who completed a course of chemotherapy, 86 (79%) achieved complete remission. Fortyβfive (52%) of patients with initial complete remission relapsed with tumour over an observation period ranging from 2 years to over 5 year