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Burger's Medicinal Chemistry and Drug Discovery || ADMET In Vitro Profiling: Utility and Applications in Lead Discovery

โœ Scribed by Abraham, Donald J.


Book ID
120494446
Publisher
John Wiley & Sons, Inc.
Year
2010
Weight
331 KB
Category
Article
ISBN-13
9780471266945

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[Methods and Principles in Medicinal Che
โœ Faller, Bernard; Urban, Laszlo ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Wiley ๐ŸŒ German โš– 310 KB

The enormous cost incurred when a candidate drug fails in a clinical trial because of poor pharmacological parameters or severe side effects makes it imperative to screen for "safe" drugs in the very early stages of drug development. Various biochemical and other in vitro assays are thus used in con