Bullous pemphigoid masquerading as porphyria cutanea tarda in a patient on haemodialysis

Effect of iron and ascorbate on uroporph

Effect of iron and ascorbate on uroporphyria in ascorbate-requiring mice as a model for porphyria cutanea tarda

✍ Nadia Gorman; Adrian Zaharia; Heidi S. Trask; Juliana G. Szakacs; Nicholas J. Ja 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 625 KB

Excess hepatic iron is known to enhance both porphyria cutanea tarda (PCT) and experimental uroporphyria. Since previous studies have suggested a role for ascorbate (AA) in suppressing uroporphyria in AA-requiring rats (in the absence of excess iron), the present study investigated whether AA could