Bulky disease is an adverse prognostic factor in patients treated with chemotherapy comprised of cyclophosphamide, doxorubicin, vincristine, and prednisone with or without radiotherapy for aggressive lymphoma

Results with chemotherapy comprised of c

Results with chemotherapy comprised of cyclophosphamide, doxorubicin, vincristine, and prednisone followed by radiotherapy with or without prechemotherapy surgical debulking for patients with bulky, aggressive lymphoma

✍ Richard B. Wilder; Jorge E. Romaguera; Susan L. Tucker; Chul S. Ha; Mark A. Hess 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB

## Abstract ## BACKGROUND The authors performed a case–control analysis of local control, progression free survival, and overall survival in patients with Stage I–II aggressive lymphomas measuring ≥ 7 cm in greatest dimension who were treated initially with or without surgical debulking: All patie