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Building BLOCK Strategies for the Synthesis of Molecular Clefts with Inside Functionality

✍ Scribed by Warrener, Ronald N.; Margetic, Davor; Amarasekara, Ananda S.; Butler, Douglas N.; Mahadevan, Indu B.; Russell, Richard A.

Book ID
120434758
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
85 KB
Volume
1
Category
Article
ISSN
1523-7060

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## Abstract We report a full account of our work towards the total synthesis of (βˆ’)‐terpestacin (**1**), a sesterterpene originally isolated from fungal strain __Arthrinium__ sp. FA1744. Its promising anti‐HIV and anti‐cancer activity, as well as its novel structure, make terpestacin an attractive