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Buffered lidocaine as a local anesthetic: An investigation of shelf life

โœ Scribed by Joel M Bartfield; Peter J Homer; David T Ford; Philip Sternklar

Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
252 KB
Volume
21
Category
Article
ISSN
1097-6760

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โœฆ Synopsis

Interventions: Three buffered lidocaine solutions prepared seven days, one day, and just before use were compared with a control solution. Subjects received 0.5 mL intradermal injections of each solution. Pain of infiltration and extent and duration of anesthesia were measured.

Measurements and main results: Pain of infiltration was less with all buffered solutions than control (P< .0001 ). Mean maximum diameter of anesthesia ranged from 29 to 33 mm for the buffered solutions compared with 31 mm for control. Mean duration of anesthesia was 33 minutes for control and 30 minutes for all of the buffered solutions. There was no statistically significant difference in extent or duration of anesthesia for any of the solutions (P> .5, p = .15 for c5 = 10%). Conclusion: Buffered lidocaine stays effective for up to one week after preparation. It is therefore convenient to use in emergency settings. [

๐Ÿ“œ SIMILAR VOLUMES

Buffered versus plain lidocaine as a loc
Buffered versus plain lidocaine as a local anesthetic for simple laceration repair
โœ Joel M Bartfield; Paul Gennis; Joseph Barbera; Brenda Breuer; E John Gallagher ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 319 KB

## Buffered lidocaine was compared with plain lidocaine as a local anesthetic for simple lacerations. Design: Randomized, double-blind, prospective clinical trial. Setting: Urban emergency department. Type of participants: Ninety-one adult patients with simple linear lacerations were enrolled. P