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Buccoadhesive oxycodone hydrochloride disks: plasma pharmacokinetics in healthy volunteers and clinical study

โœ Scribed by Brunella Parodi; Eleonora Russo; Gabriele Caviglioli; Marisa Vallarino; Flavio Fusco; Franco Henriquet


Book ID
117639895
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
622 KB
Volume
44
Category
Article
ISSN
0939-6411

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## Abstract A rapid, simple and validated liquid chromatography coupled to tandem mass spectrometric method (LCโ€MS/MS) for topiramate analysis in human plasma has been applied to pharmacokinetic and bioequivalence studies in 24 healthy male Korean volunteers. The procedure involves a simple liquid