Brønsted acid-catalyzed aza Diels-Alder reaction of Danishefsky's diene with aldimine generated in situ from aldehyde and amine in aqueous media

✍ Scribed by Takahiko Akiyama; Jun Takaya; Hirotaka Kagoshima

• Book ID: 104262408
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 197 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01630-5

✦ Synopsis

Three-component aza Diels-Alder reaction, starting from aldehyde, aniline, and Danishefsky's diene, took place smoothly under the influence of HBF4 in aqueous media to afford dihydro-4-pyridone derivatives in high yields.