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Brucella abortus nicotinamidase (PncA) contributes to its intracellular replication and infectivity in mice

✍ Scribed by Suk Kim; Daisuke Kurokawa; Kenta Watanabe; Sou-ichi Makino; Toshikazu Shirahata; Masahisa Watarai


Book ID
109327842
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
244 KB
Volume
234
Category
Article
ISSN
0378-1097

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✍ Sergio C. Oliveira; Gary A. Splitter πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 831 KB

## Abstract Genetically engineered mice with a targeted disruption in the Ξ²2‐microglobulin (Ξ²2‐m) gene or the H2‐I‐AΞ² chain (Ξ±Ξ²) which lack functional CD8^+^ or CD4^+^ T cells, respectively, were used to assess the role of T cell subsets in __Brucella abortus__ infection. Murine brucellosis was mar