Bronchogenic carcinoma An evaluation from autopsy data, with special reference to incidence, sex ratio, histological type, and accuracy of clinical diagnosis
✍ Scribed by Robert M. O'Neal; Kyu Taik Lee; David L. Edwards
- Publisher
- John Wiley and Sons
- Year
- 1957
- Tongue
- English
- Weight
- 455 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
HE: risirig incidence of bronchogenic carci-T noma has been a matter of great concern in recent years. T h e extent of the increase in incidence has not been well defined, but the most reliable data are probably those obtained from autopsy seriese5 Gilliamz ha5 recently suggested that part of the apparent increase in incidence could be due to faulty diagnosis and certification of death, especially during the period before antibiotics were available; many patients could have died of secondary respiratory infections before the underlying cancer of the lung was clinically evident. Gilliam also pointed out that if no real increase in incidence of carcinoma of the lung has occurred, diagnostic errors must have been more frequent among men than women and more frequent among the older than the younger age group. Additional data should be helplul in evaluating this problem.
T h e purpose of this report is 10 present the results of an analysis of patients with bronchogenic carcinoma autopsied in the Department of Pathology at Washington University during the years 1910 to 1954. No attcmpt will be made to reliew exten~ively the mas3 of data accumulated hy other investigator^.^, lo, l1 hIA'lERIAL AND hIETHODS T h e records of patients from Barnes Hospital autopsied in the Department of Pathology during the period 1910 to I951 were reviewed. These autopsies include 8,183 adults more than 20 years of age. T h e patients with a diagnosis of carcinoma of the lung were selected for detailed study. T h e microsections from these patients were re-examined and the