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Bromodeoxyuridine Induces Senescence in Neural Stem and Progenitor Cells

✍ Scribed by Heather H. Ross; Lindsay H. Levkoff; Gregory P. Marshall II; Maria Caldeira; Dennis A. Steindler; Brent A. Reynolds; Eric D. Laywell

Book ID
111845766
Publisher
AlphaMed Press
Year
2008
Tongue
English
Weight
994 KB
Volume
26
Category
Article
ISSN
1066-5099

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## Abstract Neural stem cells reside in defined areas of the adult mammalian brain, including the dentate gyrus of the hippocampus. Rat neural stem/progenitor cells (NSPCs) isolated from this region retain their multipotency in vitro and in vivo after grafting into the adult brain. Recent studies h