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Bromocriptine Markedly Suppresses Levodopa-Induced Abnormal Increase of Dopamine Turnover in the Parkinsonian Striatum

✍ Scribed by Norio Ogawa; Ken-ichi Tanaka; Masato Asanuma

Book ID
110251177
Publisher
Springer
Year
2000
Tongue
English
Weight
32 KB
Volume
25
Category
Article
ISSN
0364-3190

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## Abstract Brain samples from 14 Parkinson's disease patients, 10 of whom developed motor complications (dyskinesias and/or wearing‐off) on dopaminomimetic therapy, and 11 controls were analyzed. Striatal 3β‐(4‐^125^I‐iodophenyl)tropane‐2β‐carboxylic acid isopropyl ester ([^125^I]RTI‐121) ‐specifi