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Bromelain treatment reduces CD25 expression on activated CD4+ T cells in vitro

✍ Scribed by Eric R. Secor Jr.; Anurag Singh; Linda A. Guernsey; Jeff T. McNamara; Lijun Zhan; Nilanjana Maulik; Roger S. Thrall


Book ID
116576485
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
796 KB
Volume
9
Category
Article
ISSN
1567-5769

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We have further characterized the in vitro phenotype and function of anergic and suppressive CD4(+)25(+) T cells. Following TCR ligation, DO.11.10 CD4(+)25(+) T cells suppress the activation of OT-1 CD8(+)25(-) T cells in an antigen nonspecific manner. Although suppression was seen when using a mixt