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Broadening by acridine orange of the thermal transition of DNA

✍ Scribed by Charles R. Stewart

Publisher: Wiley (John Wiley & Sons)
Year: 1968
Tongue: English
Weight: 359 KB
Volume: 6
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.1968.360061208

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✦ Synopsis

Ai:riditie Orange, at, appropriate iirtermediat,e concentrations, causes a substantial broadening of the thermal transitions of Bacillus subtilis DNA and of dAT. Experiments in which the two polymers are heated together show that the broadening is the result of the transfer of acridine orange molecules from denatured to native DNA nroleclllea.

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