## Objectives To identify tasks that were sensitive to a temporary decline in cognitive performance after sleep deprivation and to investigate the ability of the acetylcholinesterase inhibitor donepezil to reverse any sleep deprivation‐induced impairment. ## Methods Thirty healthy volunteers were
Bright Light and LEET Effects on Circadian Rhythms, Sleep and Cognitive Performance
✍ Scribed by Kelly, Tamsin Lisa ;Kripke, Daniel F. ;Hayduk, Roza ;Ryman, David ;Pasche, Boris ;Barbault, Alexandre
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 141 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0748-8386
No coin nor oath required. For personal study only.
✦ Synopsis
Shift work and jet lag can disrupt circadian rhythms, with detrimental eects on alertness, performance and sleep. This study examined the eects of two interventions to adapt circadian rhythms, sleep and performance to a 10-h phase delay of the work±rest cycle. Bright light was administered from 2200 to 0200 each night to promote phase delay of circadian rhythms. Low energy emission therapy (LEET) was administered for 20 min prior to daytime sleep periods to promote sleep. Twelve subjects received bright light, 12 subjects received LEET, 11 received both interventions and 10 control subjects received only placebo treatments. Bright light accelerated phase delay of the circadian melatonin rhythm after the work±rest schedule shift. Further, subjects who received bright light had greater total sleep time (TST) and improved sleep continuity. LEET treatment produced a trend ( p 0X16) for increased TST, but LEET did not aect the melatonin circadian rhythm. After the schedule shift, cognitive performance measures showed few signi®cant dierences. Some minor improvements in cognitive performance were produced by light treatments but not by LEET.
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