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Bridgehead nitrogen heterocycles which contain the quinazoline moiety – synthesis and cycloaddition of 1,2-dihydroquinazoline 3-oxides

✍ Scribed by Heaney, Frances; McCarthy, Tomas; Mahon, Mary; McKee, V.


Book ID
119960490
Publisher
Royal Society of Chemistry
Year
2005
Tongue
English
Weight
552 KB
Volume
3
Category
Article
ISSN
1477-0520

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## Abstract The reaction of 2H‐2‐oxobenzo[b]pyran‐3‐hydrazide (**2**) with carbon disulfide in basic DMF afforded potassium thiocarbamate **3**, which readily underwent heterocyclization upon its reaction with hydrazine and/or phenacyl bromide to yield 1,2,4‐tiazole (**4**) and thiazole 7 derivativ