Breslow thickness and Clark level in melanoma : Support for including level in pathology reports and in American Joint Committee on Cancer Staging
✍ Scribed by Ashfaq A. Marghoob; Karen Koenig; Flavia V. Bittencourt; Alfred W. Kopf; Robert S. Bart
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 78 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
BACKGROUND.
Thickness is known to be an important survival prognosticator for cutaneous melanoma, but controversy exists as to whether Clark level of invasion retains prognostic significance once thickness has been accounted for. A recent proposal to eliminate Clark level from the staging system for melanoma of the American Joint Committee on Cancer (AJCC) prompted the authors to investigate whether level adds useful prognostic information to Breslow thickness. They used the data base of the New York University Melanoma Cooperative Group (NYU-MCG) Registry.