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Breast conservation: Predictors and treatment of local recurrence

โœ Scribed by Kevin P. Bethke

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
761 KB
Volume
12
Category
Article
ISSN
8756-0437

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โœฆ Synopsis

Breast conservation therapy has become the preferred treatment for many Stage I and I1 breast cancers as the "Halstedian" theory of sequential spread has been replaced by the belief that breast cancer is a systemic disease and that local-regional therapy has little impact on overall survival. Local recurrence after conservation therapy is reportedly dependent upon a number of pathological, clinical, and treatment factors. This review examines the complex relationships among these factors, their ability to predict for residual disease within the breast, and its correlation with risk for local recurrence. A local recurrence does not appear to affect overall survival, and salvage therapy provides excellent local control in the majority of cases. The proper salvage therapy is evolving, with mastectomy the current standard. However, repeat wide-excision surgery may offer good local control in a select group of patients. @ 1996 Wiley-Liss. Inc.

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## Background: Controversy exists concerning the roles of mammography and physical examination in the detection of local recurrence after conservation therapy for breast carcinoma. in addition, the prognostic factors for and optimal treatment of patients with local recurrence are uncertain. ## Met