## BACKGROUND. The purpose of this investigation was to elucidate the clinicopathologic characteristics of BRCA1-and BRCA2-associated hereditary breast carcinomas (HBCs) in Japanese women.
Breast carcinoma in carriers of BRCA1 or BRCA2 mutations : Implications of proposed distinct histologic phenotypes
β Scribed by Kelly-Anne Phillips
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 45 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## BACKGROUND. There is a clear and growing need for data regarding BRCA1 and BRCA2 mutation frequencies among breast carcinoma cases not specifically ascertained on the basis of extreme family history profiles. Toward this end, the authors previously reported results with regard to BRCA1 in breast
Germline mutations within the adenomatous polyposis coli (APC) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations within thi