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Breast cancer stem cells and epithelial mesenchymal plasticity – Implications for chemoresistance

✍ Scribed by Pinto, Cletus A.; Widodo, Edwin; Waltham, Mark; Thompson, Erik W.

Book ID
121449008
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
619 KB
Volume
341
Category
Article
ISSN
0304-3835

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## Abstract Cancer stem cells (CSCs) are similar to normal stem cells in their ability to self‐renew and to generate large populations of more differentiated descendants. In contrast to the hierarchical organization that is presumed to be the prevalent mode of normal tissue homeostasis, phenotypic